Antibody and recombinant protein manufacturing

Antibody/protein production

Abcrux Biofactory can handle a wide range of production scales and quantities, from a minimum of 5mL to 7L culture in a fermenter/bioreactor.
For transient production using cell culture, we provide clean antibodies/proteins using endotoxin-free/animal-free plasmids produced in-house.

Production using microorganisms such as E. coli and yeast

  • Shake Flask Culture
    125mL ~ 5L Flask

  • 10L Fermenter

Cell culture production (transient expression/stable production strains)

  • 5~25mL/50mL centrifuge tube

    ×100 types

  • 0.25L/1L flask

    ×24 types

  • Bioreactor 10L capacity

  • Chromatographic purification

    ※We also support manufacturing using stable production strains. Please provide the cell line only for the first order.

purification

  • Bioprocess Column (BPG)

  • For pilot scale preparative use
    Chromatography (AKTA pilot)

  • For lab-scale preparative use
    Chromatography (AKTA pure)

Work content/model case
(For transient expression in cell culture)

Establishment of stable antibody/protein production strains

With both animal-free plasmids manufactured in accordance with Standards for Biological Raw Materials, and serum-free medium, ABCRUX enables consistent animal-free establishment of stable production strains.

If a stable production strain is established using a serum-free medium and suspension CHO cells from the time of gene transfer, acclimation and suspension operations are no longer required, which is a great advantage for scale-up culture and purification.

ABCRUX also provides services for culture at various scales, acquisition of purified antibodies and proteins, and production of cell banks.

0.25L/1L flask

Work content/Model case
(Establishment of stable antibody/protein production strains)